Myocarditis

2022 - 8 - 30

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Image courtesy of "Wiley"

An autopsy case of fulminant myocarditis after severe acute ... (Wiley)

Abstract A 61-year-old woman without significant medical history developed fever 3 days after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

The infiltration of eosinophils in addition to T-cells and macrophages is noted in two case of myocarditis after SARS-CoV-2 vaccination, We hope the accumulation of detailed immunological and histopathological analyses of similar cases in the near future. Histologically, viral myocarditis has been reported to have an inflammatory picture with the infiltration of macrophages and cytotoxic T-cells (CTLs). [12](#pin13267-bib-0012) The patient's condition began to worsen 3 days after the first inoculation of the vaccine, and over the next few days, the course of the disease became fatal. Centrilobular necrosis of the liver (Figure [3c](#pin13267-fig-0003)), acute tubular necrosis of the kidney (results not shown), and severe pulmonary congestion (Figure [3a](#pin13267-fig-0003)) were observed, and there were consistent findings in various organs of the body as changes associated with biventricular heart failure due to myocarditis. In addition, there were hemophagocytic images in the bone marrow and lymph nodes, suggesting the coexistence of hypercytokinemia. [3a](#pin13267-fig-0003)), and small fibrin thrombi were visible in the lumen of the pulmonary arteries (Figure [3b](#pin13267-fig-0003)). [3](#pin13267-bib-0003), [4](#pin13267-bib-0004) The incidence of myocarditis after mRNA vaccination was higher in younger males, and the severity of myocarditis reported was mostly mild to moderate, and most of the patients were discharged with the improvement of symptoms. Eosinophils were rarely observed and giant cells were not observed in myocarditis lesion (Figure [1e](#pin13267-fig-0001)). Mild fibrosis and slight infiltration of lymphocytes and macrophages were observed in the epicardium, confirming the diagnosis of pericarditis (results not shown). The inflammatory infiltrates adjacent to the damaged cardiomyocytes were predominantly lymphocytes and macrophages (Figure [1c](#pin13267-fig-0001)). The myocarditis showed severe inflammatory cell infiltration with T-lymphocyte and macrophage predominance, and in addition to the inflammatory cells described above, vast nuclear dust accompanying neutrophilic infiltration was observed.

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Image courtesy of "Otago Daily Times"

Vaccine death inquiry: Ministry defends advice on myocarditis (Otago Daily Times)

The Ministry of Health has defended its processes, telling an inquiry into the death of a Dunedin man that Covid-19 vaccinators were adequately informed ...

Yesterday, the vaccinator who treated Mr Nairn told the inquiry she was aware that myocarditis could be a rare side effect of the vaccine, but she had been unaware it could be fatal. Both the names of the pharmacy and the pharmacist who administered the vaccine to Mr Nairn are suppressed. She was not aware of any other rare side effects of the Pfizer vaccine that needed to be raised with patients, and not every rare side effect was expected to be discussed, Ms Nolan said. Mr Parker asked her if there was a disjunct between the written information given to patients, and the information clinicians were expected to discuss as part of the informed consent process, in particular why the risk of myocarditis was considered important enough to be raised verbally but not enough to be emphasised in the pamphlet. The purpose of the inquiry was to establish the facts and consider recommendations that could avoid future such incidents, she said. It was accepted that Mr Nairn had died of myocarditis, an inflammation of the heart muscle, likely due to receiving the Pfizer vaccine.

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Image courtesy of "RNZ"

Pharmacy owner missed warning about myocarditis, inquest hears (RNZ)

A warning about the risk of myocarditis following the Covid-19 vaccine was missed by the owner of the pharmacy where Dunedin man Rory Nairn was vaccinated.

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Image courtesy of "Stuff.co.nz"

Pharmacy hasn't done an internal review since suspected vaccine ... (Stuff.co.nz)

A Heath Ministry employee says the pharmacy that administered Rory Nairn's vaccine had a responsibility to keep up to date with the latest advice, ...

[(CARM) following Covid vaccinations](https://www.medsafe.govt.nz/COVID-19/safety-report-44.asp). Wilson said she heard his body fall to the floor. She believed the Southern District Health Board ( And those articles are free. [his death was “consistent with vaccine-related myocarditis”](https://www.stuff.co.nz/national/health/coronavirus/127337216/covid19-myocarditis-was-probably-due-to-vaccination-says-board-reviewing-mans-death). [now part of Te Whatu Ora](https://www.stuff.co.nz/national/health/129730682/new-health-authority-accused-of-operating-in-secret-over-closeddoor-meetings)) would offer instructions. [The vaccine is considered the probable cause](https://www.stuff.co.nz/national/health/coronavirus/127337216/covid19-myocarditis-was-probably-due-to-vaccination-says-board-reviewing-mans-death?rm=a) in Nairn’s case. [Covid-19: 'Myocarditis was probably due to vaccination', says board reviewing man's death](https://www.stuff.co.nz/national/health/coronavirus/127337216/covid19-myocarditis-was-probably-due-to-vaccination-says-board-reviewing-mans-death?rm=a) [Covid-19: Coroner investigating after autopsy links Dunedin man's death to 'very rare' side effect of Pfizer vaccine](https://www.stuff.co.nz/national/health/coronavirus/127324992/covid19-coroner-investigating-after-autopsy-links-dunedin-mans-death-to-very-rare-side-effect-of-pfizer-vaccine?rm=a) [the second day of the coronial inquest](https://www.stuff.co.nz/national/health/coronavirus/129711704/fiancee-tells-inquest-into-suspected-vaccine-death-of-watching-the-love-of-my-life-die) into the death of the 26-year-old Dunedin man on November 17. [died in his home nearly two weeks later](https://www.stuff.co.nz/national/health/coronavirus/127324992/covid19-coroner-investigating-after-autopsy-links-dunedin-mans-death-to-very-rare-side-effect-of-pfizer-vaccine?rm=a) from myocarditis, or inflammation of the heart muscle. [Covid-19 outbreak situation report: What happened today, Monday December 20](https://www.stuff.co.nz/national/health/coronavirus/300482600/covid19-outbreak-situation-report-what-happened-today-monday-december-20?rm=a)

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Image courtesy of "New Zealand Herald"

'Our whole lives ahead of us': Death of man after Covid jab 'so ... (New Zealand Herald)

Plumber Rory James Nairn, 26, died of myocarditis in the home he shared with his fiancee, Ashleigh Wilson, on November 17 last year, 12 days after receiving his ...

Wilson said she heard a heaving sound, which she thought was Nairn vomiting but found he had collapsed in the bathroom. [It is] unfortunate Mr Nairn had to pass away for that to happen," she said. She had not been instructed by her employer to inform clients about it as a specific risk, she said. His death was so needless and could have been prevented," she said. "Rory and I had our whole lives ahead of us and so much to look forward to together. Wilson said the man she had known since the age of 14 was "vaccine-hesitant" but decided to get the jab after a celebratory breakfast following the purchase of their dream home.

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Image courtesy of "SunLive"

SunLive - Covid vaccine: Inquest into man's death continues - The ... (SunLive)

Rory Nairn died last November, less than a fortnight after receiving his first Pfizer dose. A six-day inquest into his death is being held in Dunedin District ...

"Some Covid-19 vaccines, including the Pfizer vaccine, increase the risk of myocarditis... "Rory and I were experiencing the happiest time of our lives. of our lives". It's just unfortunate that Mr Nairn had to pass away for that to happen," she said, choking back tears. Rory was my first boyfriend," Wilson said. It was not standard practice for the vaccinators at the pharmacy, where Nairn received the vaccine, to specifically warn patients about the risk of myocarditis following vaccination at the time when he received his first dose.

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Image courtesy of "One News Page"

'Our whole lives ahead of us': Death of Rory Nairn after Covid jab 'so ... (One News Page)

There were tears, along with a photo of happier times, at the inquest into the death of a Dunedin man.. • Asia-Pacific • One News Page: Tuesday, ...

Post cover
Image courtesy of "Wiley"

An autopsy case of fulminant myocarditis after severe acute ... (Wiley)

Abstract A 61-year-old woman without significant medical history developed fever 3 days after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

The infiltration of eosinophils in addition to T-cells and macrophages is noted in two case of myocarditis after SARS-CoV-2 vaccination, We hope the accumulation of detailed immunological and histopathological analyses of similar cases in the near future. Histologically, viral myocarditis has been reported to have an inflammatory picture with the infiltration of macrophages and cytotoxic T-cells (CTLs). [12](#pin13267-bib-0012) The patient's condition began to worsen 3 days after the first inoculation of the vaccine, and over the next few days, the course of the disease became fatal. Centrilobular necrosis of the liver (Figure [3c](#pin13267-fig-0003)), acute tubular necrosis of the kidney (results not shown), and severe pulmonary congestion (Figure [3a](#pin13267-fig-0003)) were observed, and there were consistent findings in various organs of the body as changes associated with biventricular heart failure due to myocarditis. In addition, there were hemophagocytic images in the bone marrow and lymph nodes, suggesting the coexistence of hypercytokinemia. [3a](#pin13267-fig-0003)), and small fibrin thrombi were visible in the lumen of the pulmonary arteries (Figure [3b](#pin13267-fig-0003)). [3](#pin13267-bib-0003), [4](#pin13267-bib-0004) The incidence of myocarditis after mRNA vaccination was higher in younger males, and the severity of myocarditis reported was mostly mild to moderate, and most of the patients were discharged with the improvement of symptoms. Eosinophils were rarely observed and giant cells were not observed in myocarditis lesion (Figure [1e](#pin13267-fig-0001)). Mild fibrosis and slight infiltration of lymphocytes and macrophages were observed in the epicardium, confirming the diagnosis of pericarditis (results not shown). The inflammatory infiltrates adjacent to the damaged cardiomyocytes were predominantly lymphocytes and macrophages (Figure [1c](#pin13267-fig-0001)). The myocarditis showed severe inflammatory cell infiltration with T-lymphocyte and macrophage predominance, and in addition to the inflammatory cells described above, vast nuclear dust accompanying neutrophilic infiltration was observed.

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Image courtesy of "New Zealand Doctor Online"

Coronial inquest into vaccine death not a pharmacist 'witch hunt' (New Zealand Doctor Online)

Vaccination expert Nikki Turner says the vaccine-related death of a Dunedin man is a reminder that all vaccinators must be cautious when seeking informed ...

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Image courtesy of "1 News"

MOH gave warning about myocarditis risk before Dunedin man's death (1 News)

The inquest into a Dunedin man's death after he got the Covid-19 vaccine has heard vaccinators were warned about serious side effects such as myocarditis.

The other effects the muscles of your heart which is the myocarditis, each of them has different investigations we can do to determine if that’s what’s going on," Royal NZ College of GPs president Dr Samantha Murton told 1News. Myocarditis and pericarditis are rare side effects involving the heart. These guidelines are based on the best scientific evidence available at the time of publication, from published and unpublished literature. “It was important to ask if the person had been exposed to or had diagnosis of myocarditis or pericarditis because that would be an indication that they should avoid Pfizer,” said Nolan. Nolan stated myocarditis would be raised “because of the risk” and it should have formed part of the informed consent discussion. To which Nolan replied: “the rare and serious also need to be explained because that is something that may not happen very often, but the rare nature is what needs to be explained to the consumer as well because they need to take action if it occurs.”

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Image courtesy of "New Zealand Herald"

Vaccine death inquiry: Ministry defends advice on myocarditis (New Zealand Herald)

The inquiry into the death of Rory Nairn is in its second day in Dunedin.

She said she was not aware of any other rare side effects that needed to be raised with patients, and not every rare side effect was expected to be discussed. Yesterday, the vaccinator who treated Nairn told the inquiry she was aware that myocarditis could be a rare side-effect of the vaccine, but she had been unaware it could be fatal. It was put to her that if the risk of a specific rare side-effect had to be spelled out, it would be expected to be very clear. "I think the communication that came though highlighted that this was a rare and serious risk," Nolan said. The purpose of the inquiry was to establish the facts and consider recommendations that could avoid future such incidents, she said. Nolan replied that a discussion about risks and potential side effects was expected to happen as part of the informed consent process, but it would not have necessarily covered all known side effects.

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