Monkeypox

Seven of the new cases are in Tāmaki Makaurau and two are in the Wellington region. The Health Ministry said an increase in cases over the past week was ...

It may not be MPX, as many illnesses can cause similar symptoms, but it's still important to get it checked." Seven of the new cases are in Tāmaki Makaurau and two are in the Wellington region. The Ministry of Health has today confirmed nine new community cases of monkeypox, bringing the total confirmed cases to 20.

Te Whatu Ora – Health New Zealand and Manatū Hauora - Ministry of Health have confirmed nine new cases of Monkeypox (MPX) as at 0915am 12 October.

The general risk of contracting MPX in New Zealand remains low. This includes guidelines and advice on potential symptoms and how to access testing. All GPs have patients with fertility problems who, at some point, may need advice, investigations organised and appropriate referral.

Health officials on Wednesday have announced nine new monkeypox (MPX) cases in New Zealand, with all of the patients being infected through community ...

The nine new cases - seven in Auckland and two in Wellington - were all deemed as community transmission, bringing the total to 20.

[will develop a rash](https://www.cdc.gov/poxvirus/monkeypox/index.html), spots or blisters at the infection site. It may not be MPX, as many illnesses can cause similar symptoms, but it’s still important to get it checked, officials say. [in the global outbreak to date](https://www.who.int/publications/m/item/multi-country-outbreak-of-monkeypox--external-situation-report--7---5-october-2022). [first cases of MPX community transmission](https://www.stuff.co.nz/national/health/300706640/monkeypox-community-transmission-confirmed-in-new-zealand?rm=a) – two cases in Auckland – were announced just last Thursday. [Monkeypox: Community transmission confirmed in New Zealand](https://www.stuff.co.nz/national/health/300706640/monkeypox-community-transmission-confirmed-in-new-zealand?rm=a) [remains low](https://www.tewhatuora.govt.nz/about-us/news-and-updates/nine-new-monkeypox-cases-in-new-zealand/), health officials say. [that not enough testing is being done for MPX](https://www.stuff.co.nz/national/health/300707315/monkeypox-vaccine-not-expected-in-nz-until-december-as-community-spread-confirmed?rm=a), and that this needed to be widened to get a handle on the extent of community spread. [until at least December.](https://www.stuff.co.nz/national/health/300707315/monkeypox-vaccine-not-expected-in-nz-until-december-as-community-spread-confirmed?rm=a) [Monkeypox vaccine not expected in NZ until December as community spread confirmed](https://www.stuff.co.nz/national/health/300707315/monkeypox-vaccine-not-expected-in-nz-until-december-as-community-spread-confirmed?rm=a) [reported on Wednesday.](https://www.tewhatuora.govt.nz/about-us/news-and-updates/nine-new-monkeypox-cases-in-new-zealand/) This brings the total number of confirmed cases in the current MPX outbreak (both active and recovered) to 20, Te Whatu Ora (Health New Zealand) and the Ministry of Health [monkeypox](https://www.health.govt.nz/our-work/diseases-and-conditions/monkeypox-mpx) in Aotearoa, officials have advised.

The Health Service Executive intends on completing monkeypox vaccinations for high priority groups by the end of the year.

The Oireachtas Committee on Health will hear later today that the aim is to complete vaccinations for high priority groups between now and December. The roll-out to high priority groups is already under way, however Monday will mark a significant expansion. The Health Service Executive intends on completing monkeypox vaccinations for high priority groups by the end of the year.

Wellington's recorded its first community transmission of the virus - with two cases. Auckland also has seven more infections. It brings New Zealand's total ...

WELLINGTON, Oct. 12 (Xinhua) -- New Zealand confirmed nine new community transmission cases of monkeypox on Wednesday, bringing the total case number in the ...

Among them, nine cases were acquired overseas and 11 were identified as community transmission, the ministry said, adding the general risk remains very low. This brings the total to 20 confirmed cases in the country, including both active and recovered. 12 (Xinhua) -- New Zealand confirmed nine new community transmission cases of monkeypox on Wednesday, bringing the total case number in the country to 20.

Scientists were able to isolate infectious virus from 2 samples, including an air sample.

"The system allows monkeypox suspects to conduct preliminary screening from home comfort using their mobile devices. However, the authors also said their findings could have wider public health implications. [In a commentary](https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00286-5/fulltext) on the study, authors from Niger Delta University wrote, "The identification of viable monkeypox virus in air samples during bedding changes is novel and noteworthy, especially as the only confirmed case of healthcare-associated monkeypox in non-endemic countries was associated with the changing of bedding in a patient room." The rooms were occupied at various times from May 24 to Jun 17, 2022, by six patients with confirmed symptomatic monkeypox. Replication-competent virus was identified in 2 (50%) of 4 samples selected for viral isolation, including from air samples collected during bedding change, and from a swab sample of an anteroom floor, the authors said. In addition to PPE, 60 surfaces in the rooms were swabbed, and air samples were collected from patient rooms (including before and during bedding changes), anterooms, and corridors adjacent to isolation rooms, the authors said.

Specialists don't expect that this year's outbreak will cause the kind of worldwide disruption seen with COVID-19. The monkeypox virus doesn't seem to be ...

“There’s no one particular mutation in the current virus that is a smoking gun,” Lefkowitz says, in terms of making people more ill or more likely to spread the infection. It is difficult to estimate the chances of the virus becoming more transmissible in the future, Lefkowitz and others say, although that can’t be ruled out. Researchers still don’t know what animal in Africa serves as the most important monkeypox reservoir, carrying the virus and spreading it to humans. One system, from researchers at RTI International (a non-profit global research institute headquartered in Research Triangle Park, North Carolina), used information from previous outbreaks of the monkeypox virus — specifically the clade 2 outbreaks — to project what could happen with the current strain. Although evidence is scarce, records from the 2017 outbreak there suggest that monkeypox is much more deadly in many of these individuals, who often have weakened immune systems. And although the CDC releases a monthly technical report on the outbreak with a set of potential scenarios, the agency says it has only moderate confidence in its predictions. (A more deadly ‘clade 1’ virus is found in Central Africa.) It is not clear that the strain causing the current outbreak is any more intrinsically transmissible than its clade 2 ancestors; rather, a form of the virus could have reached a population whose behaviours led it to spread more rapidly, says Elliot Lefkowitz, a bioinformatician at the University of Alabama at Birmingham. The WHO hopes to acquire 60,000 test kits to ship to Africa, but it is a logistical challenge to get people tested and diagnosed. That is a small number compared with the United States’ 26,000 cases, but is almost certainly a vast undercount; it is likely that many more are being missed in Nigeria than in the United States, Ogoina says. It is also unclear whether the apparent rise in African cases reflects a true outbreak there or is the result of more thorough testing, Lewis says. The monkeypox virus doesn’t seem to be airborne like COVID-19, highly transmissible like smallpox or long-lasting in the body like HIV. [1](#ref-CR1) by the US Centers for Disease Control and Prevention (CDC) that surveyed men who have sex with men found that around half had been curbing risky sexual activity because of concerns about the virus.

Virus DNA shed by the patients was detected on 93% (56/60) of surfaces in the isolation rooms, in five of 20 air samples, and on PPE. Skin particles.

“We often forget that household dust is often stirred up and forms aerosols—those particles we see slowly moving through the air when sunlight shines through a window.” It was likely that skin particles were shed into the sheets and then dispersed in the air when they were changed, the researchers said. Virus DNA shed by the patients was detected on 93% (56/60) of surfaces in the isolation rooms, in five of 20 air samples, and on PPE. “We also know that virus is in shed skin particles and up to 50% of household dust is shed skin cells,” she added. Gould said that the detection of live virus in air samples had added to the evidence that particles circulating in the air could be a route of transmission in community or household settings. Jake Dunning, a study author and researcher in diseases at the University of Oxford, told The BMJ, “We expected to see a lot of monkeypox virus DNA in the isolation rooms based on what we know about virus shedding by patients with monkeypox, but the relatively low Ct values [monkeypox DNA cycle threshold] and the widespread distribution of DNA within some of the rooms, including the floors, was still a ‘wow’ moment when the results came back.

In hospital isolation rooms containing patients with monkeypox, viral DNA was found on multiple surfaces, personal protective equipment (PPE), ...

Prior to publication the team shared its results with those caring for patients with monkeypox admitted to hospitals in the UK, and with international partners, infectious diseases specialist networks, and public health organisations. (link is external)(opens in a new tab)](https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00257-9/fulltext) Epub ahead of print. There is no suggestion that transmission of monkeypox virus via aerosols is a common way for the infection to spread from one person to another. In addition to detecting virus DNA, the researchers were able to isolate replication-competent virus in some surface and air samples. [National Institute for Health and Care Research Health Protection Unit in Emerging and Zoonotic Infections (link is external)(opens in a new tab)](http://www.hpruezi.nihr.ac.uk/), which includes the University of Liverpool as a partner. - Changing bed linen was an activity particularly associated with detection of monkeypox virus DNA in air samples in the room. Our results suggest that changing bed linen used by hospitalised patients with monkeypox does indeed increase the risk of exposure to virus, by disturbing virus on bed linen and allowing it to be suspended in the air.’ [Dr Susan Gould](/about/people/dr-susan-gould), said ‘Our results found that changing a patient’s bedding appears to be particularly associated with an increased ability to detect monkeypox virus in air samples. Our results confirm that the strict IPC measures we follow in specialist infectious diseases centres are necessary and appropriate.’ They also investigated whether the virus was detectable in air samples from the rooms. The virus is relatively hardy and under appropriate conditions can remain infectious on surfaces for weeks, creating a potential infection risk to others. However, to date it has been unclear whether these measures are proportionate to the potential virus exposure risks.

The illness, which has been declared a public health emergency in the United States, is spread through close contact.

Globally, cases continue to decline. “Seventy thousand cases have now been reported to WHO. The illness, which has been declared a public health emergency in the United States, is spread through close contact.

A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic ...

[The Africa Centres for Disease Control and Prevention(link is external)](https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fafricacdc.org%2Fdisease-outbreak%2F&data=05%7C01%7Cjess.hiller%40nih.gov%7C5ba2ea92d4094559215008daac76af2a%7C14b77578977342d58507251ca2dc2b06%7C0%7C0%7C638011923226029459%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=xz3KJ%2BMnVezq9Hr656nvYC5rUVYiZHhRCmAQa3%2B2NII%3D&reserved=0) ( [Africa CDC)(link is external)](https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fafricacdc.org%2Fdisease-outbreak%2F&data=05%7C01%7Cjess.hiller%40nih.gov%7C5ba2ea92d4094559215008daac76af2a%7C14b77578977342d58507251ca2dc2b06%7C0%7C0%7C638011923226029459%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=xz3KJ%2BMnVezq9Hr656nvYC5rUVYiZHhRCmAQa3%2B2NII%3D&reserved=0) has reported 3,326 cases of monkeypox (165 confirmed; 3,161 suspected) and 120 deaths in the DRC from Jan. The collaboration has continued as a multilateral clinical research program composed of NIAID, the DRC Ministry of Health, INRB and INRB’s partners. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. Participants will be discharged from the hospital once all lesions have scabbed over or flaked off, and after they test negative for monkeypox virus in the blood for two days in a row. Since the 1970s, monkeypox virus has caused sporadic cases and outbreaks, primarily in the rainforest areas of central Africa, and in west Africa. “This clinical trial will yield critical information about the safety and efficacy of tecovirimat for monkeypox. Centers for Disease Control and Prevention (CDC), the Institute of Tropical Medicine Antwerp, the aid organization Alliance for International Medical Action (ALIMA) and the World Health Organization (WHO). “Monkeypox has caused a high burden of disease and death in children and adults in the Democratic Republic of the Congo, and improved treatment options are urgently needed,” said NIAID Director Anthony S. National Institutes of Health, and the DRC’s National Institute for Biomedical Research (INRB) are co-leading the trial as part of the government-to-government PALM partnership. The drug targets a protein that is found on both the virus that causes smallpox and the monkeypox virus. The National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. [monkeypox](https://www.niaid.nih.gov/diseases-conditions/monkeypox) has begun in the Democratic Republic of the Congo (DRC).

Monkeypox is a zoonotic virus from the Poxviridae family that. Monkeypox virus particles. Photo: NOBEASTSOFIERCE/SCIENCE PHOTO LI. A Te Whatu Ora manager says ...

anyone could catch monkeypox but it is spread by very close physical contact and so currently we're seeing it among the community of men who have sex with men." ["Looking at the overseas experience the numbers seem to be coming down" - Te Whatu Ora Health New Zealand clinical manager William Ranger duration 2:57](/national/programmes/morningreport/audio/2018862501/monkeypox-cases-could-rise-for-some-time) ["Looking at the overseas experience the numbers seem to be coming down" - Te Whatu Ora Health New Zealand clinical manager William Ranger](/national/programmes/morningreport/audio/2018862501/monkeypox-cases-could-rise-for-some-time) "Looking at the overseas experience the numbers seem to be coming down overseas now so what we expect to happen In New Zealand in the coming weeks is that we'll probably have more cases, probably not very high numbers before it starts to come down."

Neonatal Monkeypox Virus Infection In this report, peripartum transmission of monkeypox virus to a newborn infant is described.

[5](#) Monkeypox virus infection should be considered in the differential diagnosis of a neonatal vesicular rash. [3](#) This was a case of neonatal monkeypox virus infection after peripartum transmission within a family cluster; transplacental transmission could not be ruled out. Adenovirus was also identified in the infant’s respiratory secretions and blood. The infant’s condition worsened, and invasive ventilation was initiated. The presence of axillary lymphadenopathy, the nature of the skin lesions, and the atypical timeline of intrafamilial infection aroused concern regarding human monkeypox. S1 in the The timeline of intrafamilial infection and test results is shown in Figure S2. Nine days before the birth, the infant’s father had had a febrile illness, followed by a widespread rash; the rash resolved before the infant’s birth. We report a case of perinatally acquired monkeypox virus infection and adenovirus coinfection in a 10-day-old infant. Four days after the infant’s delivery, a similar rash developed in the mother. [2](#) The rash was initially vesicular, starting on the palms and soles and subsequently spreading to the face and trunk, and gradually became pustular (

In a statement, Te Whatu Ora and Ministry of Health said seven of the new cases were in Auckland/Tāmaki Makaurau and two were in the Wellington region. An ...

But the general risk of contracting the disease in New Zealand remained low, they said. An increase in cases over the last week was not unexpected and the growth in monkeypox case numbers in New Zealand reflected overseas trends, officials said. In a statement, Te Whatu Ora and Ministry of Health said seven of the new cases were in Auckland/Tāmaki Makaurau and two were in the Wellington region.

What is Monkeypox? Monkeypox is a viral infectious disease caused by a family of viruses called orthopoxviruses. This family of viruses includes smallpox ...

At the time of publication, most provinces experiencing monkeypox outbreaks are offering targeted vaccination campaigns. It can be provided up to 14 days following exposure, which may lessen symptoms. Employers should implement an exposure control plan (including up to date risk assessments). - Stocking and managing the distribution of personal protective equipment (PPE) The number of lesions varies from a few to several thousand. They can also be created when large droplets evaporate. It can also be transmitted through touching contaminated surfaces, like clothing, towels, or bedding. - Personal protective equipment (PPE) Monkeypox is a viral infectious disease caused by a family of viruses called orthopoxviruses. Monkeypox can also be spread through respiratory secretions. The lesions go through several stages before healing. At first, the lesions can look like pimples or blisters.

Although rare, neurologic complications of acute monkeypox virus infection, like encephalomyelitis, could present in patients.

[Two cases of monkeypox-associated encephalomyelitis — Colorado and the District of Columbia, July–August 2022](https://www.cdc.gov/mmwr/volumes/71/wr/mm7138e1.htm). Neither patient was found to have MPVX nucleic acid in the CSF, which would have proven MPVX neuroinvasion. The second case of MPVX-linked encephalomyelitis was reported in a previously healthy, presumably immunocompetent gay man in his 30s in Washington, DC — Patient B. Both of the patients had some clinical and radiographic features of acute disseminated encephalomyelitis (ADEM) — which is typically a monophasic parainfectious autoimmune demyelinating disease of the CNS that affects primarily children but can also occur in adults. Magnetic resonance imaging (MRI) of the brain and spine revealed lesions in a number of sites. MPVX typically causes a febrile illness with lymphadenopathy and a diffuse vesiculopustular rash; neurologic complications associated with the virus are rare.

A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic ...

The Africa Centres for Disease Control and Prevention (Africa CDC) has reported 3,326 cases of monkeypox (165 confirmed; 3,161 suspected) and 120 deaths in the DRC from Jan. The collaboration has continued as a multilateral clinical research program composed of NIAID, the DRC Ministry of Health, INRB and INRB's partners. NIAID and the DRC Ministry of Health established the PALM clinical research partnership in response to the 2018 Ebola outbreak in Eastern DRC. Participants will be discharged from the hospital once all lesions have scabbed over or flaked off, and after they test negative for monkeypox virus in the blood for two days in a row. The trial timeline will depend on the pace of enrollment. Since the 1970s, monkeypox virus has caused sporadic cases and outbreaks, primarily in the rainforest areas of central Africa, and in west Africa. "Monkeypox has caused a high burden of disease and death in children and adults in the Democratic Republic of the Congo, and improved treatment options are urgently needed," said NIAID Director Anthony S. Clade I, which is estimated to cause more severe disease and higher mortality than Clade IIa and Clade IIb, especially in children, is responsible for infections in the DRC. National Institutes of Health, and the DRC's National Institute for Biomedical Research (INRB) are co-leading the trial as part of the government-to-government PALM partnership. Centers for Disease Control and Prevention (CDC), the Institute of Tropical Medicine Antwerp, the aid organization Alliance for International Medical Action (ALIMA) and the World Health Organization (WHO). The drug targets a protein that is found on both the virus that causes smallpox and the monkeypox virus. The National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S.